AM-2201 (1-(5-fluoropentyl)-3-(1-naphthoyl)indole) is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor. It is part of the AM series of cannabinoids discovered by Alexandros Makriyannis at Northeastern University.
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AM-2201 is usually consumed as herbal mixtures that may contain synthetic cannabinoid chemical JWH‐018, JWH‐081 and JWH‐250, and other psychoactive substances. These chemicals can cause non‐fatal and fatal hazardous effects on users. The presence of JWH‐018, JWH‐073, and AM2201 without THC was detected in urine analysis in some cases.
To its non-selectivity, it is useful for broad ligand binding assays into the affinity (potency) and duration of action upon receptors. Affinities are Ki of 1.0nM at CB1 and 2.6nM at CB2. This vapor is useful as it contains a high surface area, enabling efficient contact when applied to a membrane containing cannabinoid receptors CB1 and CB2.
This product can be used by chemical catalog companies to analyze it using NMR, GC/MS, FTIR, or HPLC. Chemists may also use it as a primary reagent for their specific studies.
The clinical effects of most new designer drugs like AM-2201 can be described as either hallucinogenic, stimulant, or opioid-like. They may also have a combination of these effects due to designer side-chain substitutions.
Like other designer drugs the use of AM-2201 can cause strong side effects; Therefore AM-2201 is NOT FOR HUMAN CONSUMPTION but for SCIENTIFIC RESEARCH ONLY!